Nucleoside Triphosphate 15-Alkyne-dUTP is a 2'-deoxyuridine triphosphate modified at the C-5 position of the pyrimidine ring. The modifying fragment contains the terminal acetylene group attached to the nitrogen-containing base through the 15-atom linker by a C–C double bond.
15-Alkyne-dUTP is used for enzymatic incorporation of nucleosides with terminal acetylene groups into DNA. The obtained modified DNA can be further functionalized via click reaction with azide-functionalized label.
General properties
Appearance |
Clear colorless or slightly yellow liquid |
Molecular mass |
730,49 |
Brutto formula |
C24H37N4O16P3 |
Purity |
≥ 95 % (HPLC) |
Storage conditions |
12 months (from the production date) at -18°C or lower |