Primetech ALC now offers azide-modified controlled pore glass for convenient automated synthesis of 3'-azide oligonucleotides.
This solid support contains non-nucleoside linker which allows introduction of N3-group into 3'-terminus under standard DNA synthesis conditions. Obtained azide-modified oligonucleotides are suitable for further click modification with alkyne containing molecules.
Highlights
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Available as 500 and 1000 Å
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Long shelf life
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No need in special synthetic conditions
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Produces 3'-N3-oligos
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3’ azide-modified CPG is compatible with DNA and RNA synthesis
Usage
Azide-modified CPG can be used under standard conditions provided by manufacturer. Ammonia deprotection at room temperature for 24 h or at 60 °C for 6 h is recommended. After deprotection, trityl-on and trityl-off oligonucleotides can be purified by HPLC and/or PAGE.
To order the product please e-mail us.