Primetech ALC was founded in 2007 as a spin-off company in the Institute of Physical Organic Chemistry (Laboratory of Biocnjugate chemisrty) and became the first private DNA synthesis laboratory in Belarus. Our researchers worked both in Belarus and abroad and have great experience in organic synthesis, molecular biology, biochemistry, biotechnology and biomedicine.
Being a small company with up to 20 employees we cooperate with best organic chemists from the National Academy of Science in Belarus. Thus Primetech creates outstanding expertise in our R&D as well as opportunity to produce complicated products under request for our clients.
We produce reagents for DNA/RNA synthesis and modification of biomolecules for more than 10 years.
Our company supplies our reagents to 25+ countries, such as Germany, USA, Switzerland, Russia, India, Great Britain, Poland, Italy, Japan, Singapore, South Korea, New Zealand, etc. There are major players of the global oligonucleotide synthesis market among our clients.
Primetech assures its customers in the high quality of products as well as competitive prices for a wide range of widespread and exclusive reagents.
Primetech collaborates closely with research institutions in Belarus and invites to cooperation all companies and individuals in the branch of reagents for molecular biology, biochemistry, and biotechnology.
Publications, which refer to our products:
1. Duy P. Nguyen «Genetic Encoding and Labeling of Aliphatic Azides and Alkynes in Recombinant Proteins via a Pyrrolysyl-tRNA Synthetase/tRNACUA Pair and Click Chemistry», J. Am. Chem. Soc., 2009, 131 (25), pp 8720–8721
2. M. Kvach et al. «Practical Synthesis of Isomerically Pure 5- and 6-Carboxytetramethylrhodamines, Useful Dyes for DNA Probes», Bioconjugate Chem., 2009, 20 (8), pp 1673–1682
3. Igor A. Prokhorenko et al. «Phenylethynylpyrene Excimer Forming Hybridization Probes for Fluorescence SNP Detection», Methods in Molecular Biology (Clifton, N.J.), vol. 578, 2009, pp. 209-222
4. A. V. Shakhbazov et al. «Plasticity of Human Mesenchymal Stem Cell Phenotype and Expression Profile under Neurogenic Conditions », Bulletin of Experimental Biology and Medicine, Volume 147, Number 4, April 2009, pp. 513-516
5. J. Pirngruber and S. A. Johnsen. «Induced G1 cell-cycle arrest controls replication-dependent histone mRNA 3′ end processing through p21, NPAT and CDK9G1 cell-cycle arrest controls histone mRNA processing», Oncogene, 1 March 2010; doi: 10.1038/onc.2010.42
6. N.L. Vutto, T.A. Gapeeva, A.N. Pundik, T.G. Tretyakova and I.D. Volotovski. «Transgenic Belarussian-bred potato plants expressing the genes for antimicrobial peptides of the cecropin-melittin type», Russian Journal of Genetics, Volume 46, Number 12, pp.1433-1439.
7. Tsybulsky D.A., Kvach M.V., Stepanova I.A., Korshun V.A., Shmanai V.V. «4',5'-Dichloro-2',7'-dimethoxy-5(6)-carboxyfluorescein (JOE): Synthesis and Spectral Properties of Oligonucleotide Conjugates.», J. Org. Chem., 2011, [Epub ahead of print]. DOI: 10.1021/jo202229t
8. Maksim V. Kvach,[a] Alexey V. Ustinov,[b] Irina A. Stepanova,[b] Andrei D. Malakhov,[b] Mikhail V. Skorobogatyi,[b] Vadim V. Shmanai,*[a] and Vladimir A. Korshun. A Convenient Synthesis of Cyanine Dyes: Reagents for the Labeling of Biomolecules. Eur. J. Org. Chem. 2008, 2107–2117.