Molecular Formula

C₇₈H₈₉Cl₂N₄O₁₆P

Molecular Weight

1438.5 g/mol

Chemical Name

6-((6-((2R,4R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(((but-3-yn-1-yloxy)(diisopropylamino)phosphanyl)oxy)cyclopentyl)-6-oxohexyl)carbamoyl)-2',7'-Dimethoxy-4',5'-dichloro-3-oxo-3H-spiro [isobenzofuran-1,9'-xanthene]-3',6'-diyl bis(cyclohexanoate)

Mass Contribution

Appearance

Seashell colored foam

Assay

≥95% (31P NMR)

Storage Conditions

Keep in a dark and dry place at -20°C

Shelf Life

2 year

Usage

Dilution: dilute 84 mg of 6-JOE phosphoramidite Pro in 0.5mL of anhydrous acetonitrile to obtain 0.1M solution;

Oxidation: standard iodine solution is recommended;

Coupling: 6 minute coupling time is recommended;

Deprotection: use ammonium hydroxide at 60°C during 6h