CAS

198080-44-3

Molecular Formula

C₅₂H₇₆N₅O₁₁PS

Molecular Weight

1010.2 g/mol

Chemical Name

5‐[(3aS,4S,6aR)‐2‐oxo‐hexahydro‐1H‐thieno[3,4‐d]imidazolidin‐4‐yl]‐N‐[(6R)‐6‐{[bis(4‐methoxyphenyl)(phenyl)methoxy]methyl}‐4‐[bis(propan‐2‐yl)amino]‐1‐cyano‐3,5,8,11,14,17‐hexaoxa‐4‐phosphaicosan‐20‐yl]pentanamide

Appearance

Yellowish foam

Assay

≥95% (NMR)

Storage Conditions

Keep in a dark and dry place at -20°C

Usage

Dilution: dilute 100 mg of Biotin phosphoramidite TEG in
1 mL of anhydrous acetonitrile to obtain 0.1M solution

Oxidation: standard iodine solution

Coupling: 15 minute coupling time

Deprotection: cleave and deprotect as required by nucleobases

¹H NMR (CD₃CN)

Conforms to the internal standard

³¹P NMR (CD₃CN)

Conforms to the internal standard