Aminolinker-18 phosphoramidite

Aminolinker-18 phosphoramidite

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Description

Molecular Formula

C41H60N3O8P

Molecular Weight

753.92 g/mol

Mass Contribution

343.31 g/mol

Chemical Name

2-cyanoethyl (1-(4-methoxyphenyl)-1,1-diphenyl-5,8,11,14,17-pentaoxa-2-azanonadecan-19-yl) diisopropylphosphoramidite

Appearance

Colorless to yellowish viscous oil

Storage Conditions

Keep in a dark and dry place at -20°C

Usage

Diluent: Anhydrous Acetonitrile.

Coupling: No changes needed from standard method recommended by synthesizer manufacturer.

Deprotection: As with other trityl-protected amines, drying down the oligo after cleavage and deprotection without addition of an non-volatile base (for example, TRIS) will lead to loss of the Trityl protecting group..

1H NMR (CD3CN)

Conforms to the internal standard

31P NMR (CD3CN)

Conforms to the internal standard