MitoLumina 750 is a cell-permeant carbocyanine fluorescent dye specifically designed for labeling active mitochondria in live cells. It contains a mildly thiol-reactive chloromethyl group that allows it to covalently bind to mitochondrial proteins, ensuring retention even after cell fixation and permeabilization.
With excitation and emission maxima at approximately 750 and 780 nm respectively, it emits in the far red spectrum, making it ideal for multicolor fluorescence imaging alongside other probes.
MitoLumina 750 belongs to the same class of mitochondria stains as MitoTracker Deep Red FM, but has excitation and emission maxima shifted into far red region. It can be applied in cell biology, neuroscience, and cancer research to visualize mitochondrial morphology, distribution, and dynamics.
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Chemical Name |
2-((1E,3E,5E)-7-((E)-1-(4-(chloromethyl)benzyl)-3,3-dimethylindolin-2-ylidene)hepta-1,3,5-trien-1-yl)-1,3,3-trimethyl-3H-indol-1-ium tetrafluoroborate |
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Molecular Formula |
C36H38ClN2BF4 |
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Molecular Weight |
621.0 g/mol |
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Appearance |
Solid |
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Storage Conditions |
store in freezer (–5°C to –30°C) and protect from light |
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Excitation maximum |
750 nm |
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Emission maximum |
780 nm |