GalNAc CPG allows the synthesis of siRNA-GalNAc conjugate.

N-acetylgalactosamine (GalNAc) is a well-defined moiety benefiting from its high affinity with asialoglycoprotein receptor (ASGPR).

By conjugating it directly to the oligonucleotides or decorating it to a certain delivery system as a targeting moiety, GalNAc has achieved compelling successes in the development of nucleic acid therapeutics. 

Other reagents for GalNAc conjugate technology are available under request.

Product citations:

Novel Cluster and Monomer-Based GalNAc Structures Induce Effective Uptake of siRNAs in Vitro and in Vivo

 SDS GalNAc TEG CPG