FW 308.29

• NHS ester couples with primary amines at pH 7-9, producing stable amide bonds
• Maleimides react to thiol groups at pH 6.5-7.5, forming thioether linkages
• Non-cleavable, soluble in DMSO, DMF
• Aliphatic spacer has low potential for eliciting an immune response
• Increased arm length vs. analogous reagents